Progress in Medical Sciences. 2021;
5(2):(66-109)
Human Chorionic Gonadotropin As A Marker of Testicular Cancer
Óscar Iván Avendaño Solano*, Iván Darío Zuñiga Espitia, Carlos Andrés Guerrero Mejía, Helmer Jair Barrios Loaiza, Alejandro Henao Giraldo, Miyerlai Martínez Salcedo, Rodolfo Antonio Correa Gil and Lina Marcela Blandón Santamaría
Abstract
Testicular cancer is a rare disease, which usually occurs in young and middle-aged men, although it can affect
early ages. CT constitutes 2% of all neoplasms in males, being the most common neoplasm between 15 and
35 years of age. However, in recent years diagnostic measures have been described to determine this disease,
an example of this are markers such as α-fetoprotein (AFP), the β subunit of human chorionic gonadotropin
(b-hCG) and lactate dehydrogenase (LDH) that actively participate in the diagnosis, prognosis, monitoring of
the treatment and the evolution of the testicular tumor, being b-HCG the most relevant for its ability to rise in
any type of testicular tumor, and can also be observed during the treatment to test its effectiveness in germ
cell tumors or to participate in the detection of cancer recurrence after treatment has ended.
